Our cell therapy product candidate pipeline is comprised of first-in-class cellular immunotherapies for cancer and immune disorders. Our programs reflect our dedication and commitment to pioneering ground breaking science to address severe, life-threatening diseases where the unmet need is significant and the treatment options are limited.
Program | Cell Type Functionality |
Target(s) | Indication(s) | Research | PreClin | Phase 1 | Phase 2 | Phase 3 |
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iPSC-derived Cell Products | ||||||||
FT576 | iNK hnCD16 + IL15RF + CD38-KO + CAR-BCMA |
BCMA, CD38 | MM ± CD38 mAb |
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FT819 | iT CAR-19, TCR-KO |
CD19 | Hematology |
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iPSC-derived Cell Products – Cancer Immunotherapy Collaborations | ||||||||
FT825/Ono | iNK,iT | HER2; undisclosed | 2 tumor targets |
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iPSC-DERIVED CELL PRODUCTS
Program | Indication | Phase |
---|---|---|
FT500 iNK Non-engineered |
Solid tumors + CPI | 1 |
BCL + CD20 mAb | 1 | |
Solid tumors + PD-L1 mAb | 1 | |
MM + CD38 mAb | 1 | |
Solid Tumors + mAb | 1 | |
FT576 iNK hnCD16 + IL15RF + CD38-KO + CAR-BCMA |
MM ± CD38 mAb | 1 |
FT819 iT CAR-19, TCR-KO |
Hematology | 1 |
iPSC-DERIVED CELL PRODUCTS – CANCER IMMUNOTHERAPY COLLABORATIONS
Program | Indication | Phase |
---|---|---|
Ono Pharma iNK/iT |
2 tumor targets | Preclinical |
iPSC = induced pluripotent stem cell iNK = iPSC-derived NK Cell iT = iPSC-derived T cell mAb = monoclonal antibody hnCD16 = high affinity, non-cleavable CD16 Fc receptor IL15-RF = IL15 receptor fusion CD38-KO = CD38 knock-out CAR = chimeric antigen receptor TCR-KO = T-cell receptor knock-out BCL = B-cell lymphoma MM = Multiple myeloma